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The tripeptide exists intracellularly either in an oxidised glutathione disulphide (GSSG) or reduced state (GSH), and maintaining an optimal GSH:GSSG ratio in the cell is critical for prevention of oxidative damage and for cell survival (Fig

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This suppression results in a decrease in blood viscosity, which therefore decreases the resistance of blood entering the heart chamber and increases blood flow into the heart, which might be a possible mechanism of how GHK could decrease the time needed for the heart to preload the blood into the chamber [53]

Same swaps, same logic