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Though PNP-1-10-0.05 TZP exhibited slightly greater tissue response than the PNP-1-10-0.05 Sema gel, the TZP gel group still offered improved histological profiles relative to bolus injection

A 5-days-on / 2-off variant (dosing MondayFriday, resting the weekend) also appears in the research framing for those studying receptor-sensitivity preservation

For mild, non-bloody diarrhoea without fever, short-course loperamide may be considered following pharmacist or clinician advice, in line with NHS self-care guidance

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