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Neither participants reported previous testing or diagnosis regarding monogenic obesity, which is not part of our clinical standard

References include Jastreboff et al., New England Journal of Medicine , 2022 (SURMOUNT-1, tirzepatide for obesity), the FDA Zepbound prescribing information, the FDA Drug Shortages list (accessed Q1 2026), Patel et al., Annals of Pharmacotherapy , 2024 (compounded GLP-1 dosing errors), and the U.S

Patients have grown accustomed to using injectables, and doctors feel at ease prescribing them, particularly now that once-weekly formulations that improve adherence are available