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These increased levels of antifungal resistance in Candida biofilms have (at least in part) been shown to be due to up-regulation of efflux pumps (Ramage et al., 2002), gene mutations in drug-target enzymes e.g

GHK-Cu has been compared to other skincare products, such as retinol and vitamin C creams, and has shown positive effects, with some people anecdotally reporting improvements in their skin, such as reduced crow's feet, although a study on hair did not seem too promising 7m10s

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