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Notably, similar inhibitions were observed both with the wild type enzyme and its cysteine mutants, suggesting that thiol conjugation is dispensable for GST inactivation by auronofin in contrast to other described targets 103

December 2nd, 2025: December 2025 JPML Update The Ozempic lawsuit saw a rise in filings between November and December, increasing from 2,914 to 2,947 cases in the multidistrict litigation