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Kumaran KS, Prince PSM

No human studies have evaluated the effect of SGLT-2Is or GLP-1RAs on renal fibrosis

2022 Feb 1;367:109443

Longer-term observations indicate that maintaining treatment is essential to preserve weight loss, as stopping the medication often results in regaining some of the lost weight

26,27,28,29 Although experimental evidence for semaglutide-related reductions in alcohol intake remains specific to nonhuman studies, 30,31,32,33 off-label prescribing for AUD is already reported, necessitating clinical trials